eprintid: 18725 rev_number: 2 eprint_status: archive userid: 1 dir: disk0/00/01/87/25 datestamp: 2024-06-04 14:11:06 lastmod: 2024-06-04 14:11:06 status_changed: 2024-06-04 14:03:56 type: article metadata_visibility: show creators_name: Rizkiyah, D.N. creators_name: Putra, N.R. creators_name: Idham, Z. creators_name: Aziz, A.H.A. creators_name: Che Yunus, M.A. creators_name: Veza, I. creators_name: Irianto, creators_name: Chinedu Mamah, S. creators_name: Qomariyah, L. title: Recovery of Anthocyanins from Hibiscus sabdariffa L. Using a Combination of Supercritical Carbon Dioxide Extraction and Subcritical Water Extraction ispublished: pub keywords: Anthocyanins; Hemp; Supercritical fluid extraction, Bioactive compounds; Hibiscus sabdariffa; Optimisations; Particle surface; Roselle; Sub-critical water; Subcritical water extraction; Supercritical carbon dioxide extraction; Supercritical carbondioxides; Total phenolic compounds, Carbon dioxide note: cited By 8 abstract: Anthocyanins are one of the bioactive compounds in roselle that has many medicinal proposes. Anthocyanins are placed in the inner part of the roselle; therefore, combinations of two methods were applied to extract the anthocyanins. The first stage is employing supercritical carbon dioxide (ScCO2) to break the particle surface or outer layer of the roselle based on the total phenolic compounds (TPC) recovery, and the second step was to apply subcritical water extraction (SWE) for the extraction of anthocyanins. The objective is to determine the best conditions to obtain high yields of total anthocyanins compounds (TAC) from the roselle (Hibiscus sabdariffa) by employing a combination of ScCO2 and SWE. The optimal conditions of ScCO2 (first stage) were 19.13 MPa, 60 °C, and 4.31 mL/min, yielding 18.20, and 80.34 mg/100 g TPC, respectively. The optimum conditions of SWE (second stage) were 9.48 MPa, 137 °C, and 6.14 mL/min, yielding 86.11 and 1224.61 mg/100 g TAC, respectively. The application of integrated ScCO2 and SWE proved successful in achieving high anthocyanins production and yield as compared to previous extraction methods. This approach may be used to extract the roselle with a greater anthocyanin�s concentration than the prior method. © 2023 by the authors. date: 2023 official_url: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85152249497&doi=10.3390%2fpr11030751&partnerID=40&md5=b2d5c237e69f1ea210d9b43874a145b0 id_number: 10.3390/pr11030751 full_text_status: none publication: Processes volume: 11 number: 3 refereed: TRUE citation: Rizkiyah, D.N. and Putra, N.R. and Idham, Z. and Aziz, A.H.A. and Che Yunus, M.A. and Veza, I. and Irianto and Chinedu Mamah, S. and Qomariyah, L. (2023) Recovery of Anthocyanins from Hibiscus sabdariffa L. Using a Combination of Supercritical Carbon Dioxide Extraction and Subcritical Water Extraction. Processes, 11 (3).