@article{scholars18442, title = {Unlocking the potential of microalgae bio-factories for carbon dioxide mitigation: A comprehensive exploration of recent advances, key challenges, and energy-economic insights}, journal = {Bioresource Technology}, doi = {10.1016/j.biortech.2023.129094}, year = {2023}, volume = {380}, note = {cited By 10}, abstract = {Microalgae are promising alternatives to mitigate atmospheric CO2 owing to their fast growth rates, resilience in the face of adversity and ability to produce a wide range of products, including food, feed supplements, chemicals, and biofuels. However, to fully harness the potential of microalgae-based carbon capture technology, further advancements are required to overcome the associated challenges and limitations, particularly with regards to enhancing CO2 solubility in the culture medium. This review provides an in-depth analysis of the biological carbon concentrating mechanism and highlights the current approaches, including species selection, optimization of hydrodynamics, and abiotic components, aimed at improving the efficacy of CO2 solubility and biofixation. Moreover, cutting-edge strategies such as gene mutation, bubble dynamics and nanotechnology are systematically outlined to elevate the CO2 biofixation capacity of microalgal cells. The review also evaluates the energy and economic feasibility of using microalgae for CO2 bio-mitigation, including challenges and prospects for future development. {\^A}{\copyright} 2023 Elsevier Ltd}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85153619654&doi=10.1016\%2fj.biortech.2023.129094&partnerID=40&md5=bcbccdcd607d8fa8456116dc16cf0a99}, keywords = {Carbon dioxide; Chemical contamination; Microorganisms; Solubility, Atmospheric CO 2; Carbon dioxide mitigation; CO2 biofixation; Culture medium; Economic insights; Energy; Energy economics; Fast growth rate; Feed supplement; Micro-algae, Microalgae, carbon; carbon dioxide; biofuel, bioactivity; carbon dioxide; carbon emission; economic analysis; emission control; microalga; nanomaterial, absorption; biomass; carbon fixation; economics; energy; enzyme activity; gene mutation; genetic engineering; hydrodynamics; light intensity; lipid storage; microalga; nanotechnology; nonhuman; pentose phosphate cycle; pH; photosynthesis; random mutagenesis; retention time; Review; solubility; temperature; ultrastructure, Biofuels; Biomass; Carbon Dioxide; Hydrodynamics; Microalgae}, author = {Kanna Dasan, Y. and Lam, M. K. and Chai, Y. H. and Lim, J. W. and Ho, Y. C. and Tan, I. S. and Lau, S. Y. and Show, P. L. and Lee, K. T.} }