TY  - JOUR
Y1  - 2023///
VL  - 130
EP  - 733
UR  - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85160673512&doi=10.1016%2fj.procbio.2023.05.013&partnerID=40&md5=b03838f5a6a9e2228038201e975cac34
JF  - Process Biochemistry
A1  - Lim, S.W.
A1  - Kansedo, J.
A1  - Tan, I.S.
A1  - Tan, Y.H.
A1  - Nandong, J.
A1  - Lam, M.K.
A1  - Ongkudon, C.M.
AV  - none
KW  - Biochemistry; Biodegradable polymers; Conversion efficiency; Elastomers; Fermentation; Life cycle; Oils and fats; Production efficiency
KW  -  'current; Bio-plastics; Biodegradable plastics; Fermentation strategy; Kinetic study; Lipid-rich oil; Oil based; Polyhydroxyalkanoates; Production efficiency; Valorisation
KW  -  Substrates
TI  - Microbial valorization of oil-based substrates for polyhydroxyalkanoates (PHA) production â?? Current strategies, status, and perspectives
ID  - scholars18435
SP  - 715
N1  - cited By 5
N2  - With the rising interest in developing polyhydroxyalkanoate (PHA) bioplastics as an auspicious substitute for conventional plastics, the exploitation of low-cost oil substrates for PHA biosynthesis has become popular recently. In view of the paucity of feasibility studies on lipid-based PHA production, this paper aims to provide an overview of the PHA production from diverse lipid-rich sources, covering the PHA production efficiencies using different plausible fermentation strategies and the key influencing factors for oil-based PHA production. Considering the high conversion efficiency (97.5 of the theoretical PHA yield), direct fermentation of oil has shown great promise for PHA industrialization. Plant oils which could achieve a high PHA yield (0.25â??0.77 g/g) are better carbon sources than waste cooking oil (0.15â??0.28 g/g). In addition to providing information on the potential enhancement tools (i.e., mixed cultures, metabolic engineering, and kinetic studies) for lipid-based PHA production, this paper also reviews the techno-economic and life cycle assessment of PHA production in comparison to the conventional plastics. Besides, technical challenges and future perspectives for the commercialization of oil-based PHA production have been discussed (specifically targeting on the concerns of inconsistent production efficiency, complex recovery process, and high production cost), offering further insights towards developing a sustainable circular economy. © 2023
ER  -