<> "The repository administrator has not yet configured an RDF license."^^ . <> . . . "Microbial valorization of oil-based substrates for polyhydroxyalkanoates (PHA) production � Current strategies, status, and perspectives"^^ . "With the rising interest in developing polyhydroxyalkanoate (PHA) bioplastics as an auspicious substitute for conventional plastics, the exploitation of low-cost oil substrates for PHA biosynthesis has become popular recently. In view of the paucity of feasibility studies on lipid-based PHA production, this paper aims to provide an overview of the PHA production from diverse lipid-rich sources, covering the PHA production efficiencies using different plausible fermentation strategies and the key influencing factors for oil-based PHA production. Considering the high conversion efficiency (97.5 of the theoretical PHA yield), direct fermentation of oil has shown great promise for PHA industrialization. Plant oils which could achieve a high PHA yield (0.25�0.77 g/g) are better carbon sources than waste cooking oil (0.15�0.28 g/g). In addition to providing information on the potential enhancement tools (i.e., mixed cultures, metabolic engineering, and kinetic studies) for lipid-based PHA production, this paper also reviews the techno-economic and life cycle assessment of PHA production in comparison to the conventional plastics. Besides, technical challenges and future perspectives for the commercialization of oil-based PHA production have been discussed (specifically targeting on the concerns of inconsistent production efficiency, complex recovery process, and high production cost), offering further insights towards developing a sustainable circular economy. © 2023"^^ . "2023" . . "130" . . "Process Biochemistry"^^ . . . . . . . . . . . . . . . . . . . . . . . . . . "I.S."^^ . "Tan"^^ . "I.S. Tan"^^ . . "M.K."^^ . "Lam"^^ . "M.K. Lam"^^ . . "S.W."^^ . "Lim"^^ . "S.W. Lim"^^ . . "J."^^ . "Kansedo"^^ . "J. Kansedo"^^ . . "Y.H."^^ . "Tan"^^ . "Y.H. Tan"^^ . . "J."^^ . "Nandong"^^ . "J. Nandong"^^ . . "C.M."^^ . "Ongkudon"^^ . "C.M. Ongkudon"^^ . . . . . "HTML Summary of #18435 \n\nMicrobial valorization of oil-based substrates for polyhydroxyalkanoates (PHA) production � Current strategies, status, and perspectives\n\n" . "text/html" . .