eprintid: 18110
rev_number: 2
eprint_status: archive
userid: 1
dir: disk0/00/01/81/10
datestamp: 2024-06-04 14:10:13
lastmod: 2024-06-04 14:10:13
status_changed: 2024-06-04 14:01:26
type: article
metadata_visibility: show
creators_name: Husain, S.F.
creators_name: Chiang, S.K.
creators_name: Vasu, A.A.
creators_name: Goh, C.P.
creators_name: McIntyre, R.S.
creators_name: Tang, T.B.
creators_name: Tran, B.X.
creators_name: Dang, T.H.T.
creators_name: Nguyen, T.T.
creators_name: Ho, R.C.
creators_name: Ho, C.S.
title: Functional Near-Infrared Spectroscopy of English-Speaking Adults With Attention-Deficit/Hyperactivity Disorder During a Verbal Fluency Task
ispublished: pub
keywords: adult; attention deficit hyperactivity disorder; hemodynamics; human; near infrared spectroscopy; physiology; prefrontal cortex; procedures, Adult; Attention Deficit Disorder with Hyperactivity; Hemodynamics; Humans; Prefrontal Cortex; Spectroscopy, Near-Infrared
note: cited By 4
abstract: Objective: Functional near-infrared spectroscopy (fNIRS) provides direct and quantitative assessment of cortical hemodynamic response. It has been used to identify neurophysiological alterations in medication-naïve adults with attention-deficit/hyperactivity disorder (ADHD). Hence, this study aimed to distinguish both medication-naïve and medicated adults with ADHD from healthy controls (HC). Method: 75 HCs, 75 medication-naïve, and 45 medicated patients took part in this study. fNIRS signals during a verbal fluency task (VFT) were acquired using a 52-channel system and relative oxy-hemoglobin changes in the prefrontal cortex were quantified. Results: Prefrontal cortex hemodynamic response was lower in patients than HCs (p � �.001). Medication-naïve and medicated patients did not differ in hemodynamic response or symptom severity (p >.05). fNIRS measurements were not associated with any clinical variables (p >.05). 75.8 patients and 76 HCs were correctly classified using hemodynamic response. Conclusion: fNIRS may be a potential diagnostic tool for adult ADHD. These findings need to be replicated in larger validation studies. © ©The Author(s) 2023.
date: 2023
official_url: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85162761543&doi=10.1177%2f10870547231180111&partnerID=40&md5=f3f7796394d3ed9eb9dedb8dad043b8b
id_number: 10.1177/10870547231180111
full_text_status: none
publication: Journal of Attention Disorders
volume: 27
number: 13
pagerange: 1448-1459
refereed: TRUE
citation:   Husain, S.F. and Chiang, S.K. and Vasu, A.A. and Goh, C.P. and McIntyre, R.S. and Tang, T.B. and Tran, B.X. and Dang, T.H.T. and Nguyen, T.T. and Ho, R.C. and Ho, C.S.  (2023) Functional Near-Infrared Spectroscopy of English-Speaking Adults With Attention-Deficit/Hyperactivity Disorder During a Verbal Fluency Task.  Journal of Attention Disorders, 27 (13).  pp. 1448-1459.