@article{scholars18110,
           pages = {1448--1459},
         journal = {Journal of Attention Disorders},
            year = {2023},
           title = {Functional Near-Infrared Spectroscopy of English-Speaking Adults With Attention-Deficit/Hyperactivity Disorder During a Verbal Fluency Task},
             doi = {10.1177/10870547231180111},
          volume = {27},
            note = {cited By 4},
          number = {13},
          author = {Husain, S. F. and Chiang, S. K. and Vasu, A. A. and Goh, C. P. and McIntyre, R. S. and Tang, T. B. and Tran, B. X. and Dang, T. H. T. and Nguyen, T. T. and Ho, R. C. and Ho, C. S.},
        abstract = {Objective: Functional near-infrared spectroscopy (fNIRS) provides direct and quantitative assessment of cortical hemodynamic response. It has been used to identify neurophysiological alterations in medication-na{\~A}?ve adults with attention-deficit/hyperactivity disorder (ADHD). Hence, this study aimed to distinguish both medication-na{\~A}?ve and medicated adults with ADHD from healthy controls (HC). Method: 75 HCs, 75 medication-na{\~A}?ve, and 45 medicated patients took part in this study. fNIRS signals during a verbal fluency task (VFT) were acquired using a 52-channel system and relative oxy-hemoglobin changes in the prefrontal cortex were quantified. Results: Prefrontal cortex hemodynamic response was lower in patients than HCs (p {\^a}?? {\^a}??.001). Medication-na{\~A}?ve and medicated patients did not differ in hemodynamic response or symptom severity (p {\ensuremath{>}}.05). fNIRS measurements were not associated with any clinical variables (p {\ensuremath{>}}.05). 75.8 patients and 76 HCs were correctly classified using hemodynamic response. Conclusion: fNIRS may be a potential diagnostic tool for adult ADHD. These findings need to be replicated in larger validation studies. {\^A}{\copyright} {\^A}{\copyright}The Author(s) 2023.},
             url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85162761543&doi=10.1177\%2f10870547231180111&partnerID=40&md5=f3f7796394d3ed9eb9dedb8dad043b8b},
        keywords = {adult; attention deficit hyperactivity disorder; hemodynamics; human; near infrared spectroscopy; physiology; prefrontal cortex; procedures, Adult; Attention Deficit Disorder with Hyperactivity; Hemodynamics; Humans; Prefrontal Cortex; Spectroscopy, Near-Infrared}
}