eprintid: 17930
rev_number: 2
eprint_status: archive
userid: 1
dir: disk0/00/01/79/30
datestamp: 2023-12-19 03:24:14
lastmod: 2023-12-19 03:24:14
status_changed: 2023-12-19 03:08:56
type: article
metadata_visibility: show
creators_name: Letchumanan, I.
creators_name: Gopinath, S.C.B.
creators_name: Md Arshad, M.K.
creators_name: Mohamed Saheed, M.S.
creators_name: Perumal, V.
creators_name: Voon, C.H.
creators_name: Hashim, U.
title: Gold-Nanohybrid Biosensors for Analyzing Blood Circulating Clinical Biomacromolecules: Current Trend toward Future Remote Digital Monitoring
ispublished: pub
keywords: Biocompatibility; Biomarkers; Biosensors; Blood; Gold; Nanocomposites; Plasmons; Surface plasmon resonance, Bio-sensor platforms; Diagnostic methods; Digital monitoring; Disease biomarker; Electron transfer; Gold nanocomposites; Localized surface plasmon resonance; Surface-to-volume ratio, Diagnosis, biomarker; blood; digitization; gold; molecular analysis; monitoring; nanocomposite; nanoparticle; sensor; trend analysis, gold; metal nanoparticle; nanocomposite, chemistry; genetic procedures; human; procedures; surface plasmon resonance, Biosensing Techniques; Gold; Humans; Metal Nanoparticles; Nanocomposites; Surface Plasmon Resonance
note: cited By 6
abstract: Mortality level is worsening the situation worldwide thru blood diseases and greatly jeopardizes the human health with poor diagnostics. Due to the lack of successful generation of early diagnosis, the survival rate is currently lower. To overcome the present hurdle, new diagnostic methods have been choreographed for blood disease biomarkers analyses with the conjunction of ultra-small ideal gold nanohybrids. Gold-hybrids hold varieties of unique features, such as high biocompatibility, increased surface-to-volume ratio, less-toxicity, ease in electron transfer and have a greater localized surface plasmon resonance. Gold-nanocomposites can be physically hybrid on the sensor surface and functionalize with the biomolecules using appropriate chemical conjugations. Revolutionizing biosensor platform can be prominently linked for the nanocomposite applications in the current research on medical diagnosis. This review encloses the new developments in diagnosing blood biomarkers by utilizing the gold-nanohybrids. Further, the current state-of-the-art and the future envision with digital monitoring for facile telediagnosis were narrated. © 2020 Taylor & Francis Group, LLC.
date: 2022
publisher: Taylor and Francis Ltd.
official_url: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85090443106&doi=10.1080%2f10408347.2020.1812373&partnerID=40&md5=573ebab0f5078b89de49fdb9bc377c63
id_number: 10.1080/10408347.2020.1812373
full_text_status: none
publication: Critical Reviews in Analytical Chemistry
volume: 52
number: 3
pagerange: 577-592
refereed: TRUE
issn: 10408347
citation:   Letchumanan, I. and Gopinath, S.C.B. and Md Arshad, M.K. and Mohamed Saheed, M.S. and Perumal, V. and Voon, C.H. and Hashim, U.  (2022) Gold-Nanohybrid Biosensors for Analyzing Blood Circulating Clinical Biomacromolecules: Current Trend toward Future Remote Digital Monitoring.  Critical Reviews in Analytical Chemistry, 52 (3).  pp. 577-592.  ISSN 10408347