eprintid: 17168
rev_number: 2
eprint_status: archive
userid: 1
dir: disk0/00/01/71/68
datestamp: 2023-12-19 03:23:36
lastmod: 2023-12-19 03:23:36
status_changed: 2023-12-19 03:07:35
type: article
metadata_visibility: show
creators_name: Shahri, N.N.M.
creators_name: Taha, H.
creators_name: S. A. Hamid, M.H.
creators_name: Kusrini, E.
creators_name: Lim, J.-W.
creators_name: Hobley, J.
creators_name: Usman, A.
title: Antimicrobial activity of silver sulfide quantum dots functionalized with highly conjugated Schiff bases in a one-step synthesis
ispublished: pub
keywords: Bacteriology; Bioassay; Escherichia coli; Microwave integrated circuits; Semiconductor quantum dots; Sulfur compounds, Anti-microbial activity; Average size; Capping agent; Functionalized; Low dimensional; Minimum inhibitory concentration; One step synthesis; One-pot synthesis; Schiff-base; Thioglycolic acid, Silver compounds
note: cited By 9
abstract: In the present paper, low-dimensional Ag2S QDs were fabricated for the first time, with four different dithiocarbazate derivative Schiff bases (SB) as capping agents in a one-pot synthesis. These SB-capped Ag2S QDs were almost spherical with an average size range of 4.0 to 5.6 nm, which is slightly smaller than conventional thioglycolic acid (TGA)-capped Ag2S QDs. We demonstrate that the growth of Gram-positive bacteria (Bacillus subtillus and Staphylococcus aureus), Gram-negative bacteria (Escherichia coli and Pseudomonas aeruginosa), and a prevalent fungal pathogen (Candida albicans) are inhibited more when the bacterial and fungal cells were nurtured with the synthesized SB-Ag2S QDs, compared with TGA-Ag2S QDs or free unbound Schiff bases. The minimum inhibitory concentration (MIC) results confirmed that even low concentrations of SB-Ag2S QDs were able to inhibit bacterial (MIC 5-75 μg mL-1) and fungal growth (MIC 80-310 μg mL-1), and in some cases they performed better than streptomycin (8-25 μg mL-1). Lethality bioassay results confirmed that SB-Ag2S QDs were not toxic to brine shrimp (Artemia salina). The results show that capping agents are essential in the design of functional Ag2S QDs, and highlight that Schiff bases provide an excellent opportunity to optimize the biological activities of silver based QDs. © The Royal Society of Chemistry.
date: 2022
publisher: Royal Society of Chemistry
official_url: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85123840507&doi=10.1039%2fd1ra08296e&partnerID=40&md5=2e0f144c427f60258f550e3bf9b5dc21
id_number: 10.1039/d1ra08296e
full_text_status: none
publication: RSC Advances
volume: 12
number: 5
pagerange: 3136-3146
refereed: TRUE
issn: 20462069
citation:   Shahri, N.N.M. and Taha, H. and S. A. Hamid, M.H. and Kusrini, E. and Lim, J.-W. and Hobley, J. and Usman, A.  (2022) Antimicrobial activity of silver sulfide quantum dots functionalized with highly conjugated Schiff bases in a one-step synthesis.  RSC Advances, 12 (5).  pp. 3136-3146.  ISSN 20462069