eprintid: 16358 rev_number: 2 eprint_status: archive userid: 1 dir: disk0/00/01/63/58 datestamp: 2023-12-19 03:22:53 lastmod: 2023-12-19 03:22:53 status_changed: 2023-12-19 03:06:06 type: article metadata_visibility: show creators_name: Yat, Y.D. creators_name: Foo, H.C.Y. creators_name: Tan, I.S. creators_name: Lam, M.K. creators_name: Lim, S. title: Carbon dots and miniaturizing fabrication of portable carbon dot-based devices for bioimaging, biosensing, heavy metal detection and drug delivery applications ispublished: pub keywords: Biocompatibility; Carbon; Controlled drug delivery; Fabrication; Heavy metals; Optical properties; Photoluminescence; Semiconductor quantum dots; Targeted drug delivery; Wastewater treatment, Bio-imaging; Biosensing; Carbon dots; Carbonaceous nanoparticles; Classifieds; Drug delivery applications; Heavy metals detection; Metal drugs; Non-toxicity; Property, Bioimaging note: cited By 2 abstract: Carbon dots (CDs), classified as quasi-spherical carbonaceous nanoparticles, have recently gained much attention in wastewater treatment. Their superior distinctive properties, such as non-toxicity, biocompatibility and optical properties, make them a promising option compared to the conventional inorganic semiconductor quantum dots. Herein, the recent progress in CD synthesis methods and photoluminescence properties have been highlighted. Besides, the tailoring process of photoluminescence via surface functionalization is presented. Most importantly, this review aims to provide insightful knowledge on the advanced techniques to fabricate miniaturized CD-based sensing platforms for on-site and real-time analysis. These techniques can be divided into two main paths, i.e., the additive and subtractive methods as well as the combination of both with the illustration of graphical diagrams. Further, the applications of CDs in bioimaging, biosensing, heavy metal detection and drug delivery are elaborated based on the current progress of the experimental works. Lastly, the future perspective and challenges to develop and utilize the CDs are discussed accordingly. In short, this review tends to promote more research on the connection between online networks and the miniaturized property of CDs in enhancing on-site and real-time applications. © 2022 The Royal Society of Chemistry. date: 2022 publisher: Royal Society of Chemistry official_url: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85141223735&doi=10.1039%2fd2tc03230a&partnerID=40&md5=30793f00e3a6e43e4b3d0d68fec2fee2 id_number: 10.1039/d2tc03230a full_text_status: none publication: Journal of Materials Chemistry C volume: 10 number: 41 pagerange: 15277-15300 refereed: TRUE issn: 20507534 citation: Yat, Y.D. and Foo, H.C.Y. and Tan, I.S. and Lam, M.K. and Lim, S. (2022) Carbon dots and miniaturizing fabrication of portable carbon dot-based devices for bioimaging, biosensing, heavy metal detection and drug delivery applications. Journal of Materials Chemistry C, 10 (41). pp. 15277-15300. ISSN 20507534