eprintid: 16351
rev_number: 2
eprint_status: archive
userid: 1
dir: disk0/00/01/63/51
datestamp: 2023-12-19 03:22:53
lastmod: 2023-12-19 03:22:53
status_changed: 2023-12-19 03:06:05
type: article
metadata_visibility: show
creators_name: Al-Dhahebi, A.M.
creators_name: Jose, R.
creators_name: Mustapha, M.
creators_name: Saheed, M.S.M.
title: Ultrasensitive aptasensor using electrospun MXene/polyvinylidene fluoride nanofiber composite for Ochratoxin A detection
ispublished: pub
keywords: Charge transfer; Electrochemical electrodes; Fruit juices; Nanofibers, Aptasensors; Biosensor design; Electroactive material; Electrospuns; Food samples; Mycotoxin contamination; Nanofiber composites; Ochratoxin A; Piezoelectric sensors; Ultrasensitive, Fluorine compounds, aldehyde; aptamer; nanofiber; ochratoxin; polyvinylidene fluoride; sodium chloride; titanium carbide; aptamer; fluorocarbon; ochratoxin; polyvinyl derivative; polyvinylidene fluoride, Article; electrospinning; food industry; grape juice; limit of detection; limit of quantitation; electrochemical analysis; genetic procedures, Aptamers, Nucleotide; Biosensing Techniques; Electrochemical Techniques; Fluorocarbon Polymers; Limit of Detection; Nanofibers; Ochratoxins; Polyvinyls
note: cited By 23
abstract: Ochratoxin A (OTA) has harmful effects to human and animal health; therefore, sensitive and selective detection of OTA is highly demanded. Herein, an ultrasensitive electrochemical aptasensor electrode comprising electrospun MXene/polyvinylidene fluoride (Ti3C2Tx/PVDF) nanofiber composite is presented. Addition of Ti3C2Tx up to 13 effectively increased the fiber diameter and lowered the β-phase of PVDF nanofibers, consequently lowering the charge transfer resistance. The nanofiber composite is then coated on the screen-printed carbon electrode to chemically functionalized with saline and aldehyde groups for efficient aptamer loading. The optimized aptasensor demonstrated sensitive detection of OTA over the dynamic concentration range from 1 fg mL�1 to 1 ng mL�1 with a limit of detection of 2.15 fg mL�1 and quantification limit of 6.52 fg mL�1, with high selectivity. The aptasensor could detect the OTA at femtogram per milliliter concentration in grape juice samples, demonstrating its enormous potential for OTA detection in food industry. © 2022 Elsevier Ltd
date: 2022
publisher: Elsevier Ltd
official_url: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85130371663&doi=10.1016%2fj.foodchem.2022.133105&partnerID=40&md5=86fc5c616235a8266264b126078d8dda
id_number: 10.1016/j.foodchem.2022.133105
full_text_status: none
publication: Food Chemistry
volume: 390
refereed: TRUE
issn: 03088146
citation:   Al-Dhahebi, A.M. and Jose, R. and Mustapha, M. and Saheed, M.S.M.  (2022) Ultrasensitive aptasensor using electrospun MXene/polyvinylidene fluoride nanofiber composite for Ochratoxin A detection.  Food Chemistry, 390.   ISSN 03088146