relation: https://khub.utp.edu.my/scholars/16241/ title: Ultrasonic�assisted molten salt hydrates pretreated Eucheuma cottonii residues as a greener precursor for third-generation L-lactic acid production creator: Chong, S.L. creator: Tan, I.S. creator: Foo, H.C.Y. creator: Chan, Y.S. creator: Lam, M.K. creator: Lee, K.T. description: This study aims to establish an efficient pretreatment method that facilitates the conversion of sugars from macroalgae wastes, Eucheuma cottonii residues (ECRs) during hydrolysis and subsequently enhances L-lactic acid (L-LA) production. Hence, ultrasonic-assisted molten salt hydrates (UMSHs) pretreatment was proposed to enhance the accessibility of ECRs to hydrolyze into glucose through dilute acid hydrolysis (DAH). The obtained hydrolysates were employed as the substrate in producing L-LA by separate hydrolysis and fermentation (SHF). The maximum glucose yield (97.75 ) was achieved using UMSHs pretreated ECRs with 40 wt ZnCl2 at 80 °C for 2 h and followed with DAH. The optimum glucose to L-LA yield obtained for SHF was 90.08 using 5 (w/w) inoculum cell densities of B. coagulans ATCC 7050 with yeast extract (YE). A comparable performance (89.65 ) was obtained using a nutrient combination (lipid-extracted Chlorella vulgaris residues (CVRs), vitamin B3, and vitamin B5) as a partial alternative for YE. © 2022 Elsevier Ltd publisher: Elsevier Ltd date: 2022 type: Article type: PeerReviewed identifier: Chong, S.L. and Tan, I.S. and Foo, H.C.Y. and Chan, Y.S. and Lam, M.K. and Lee, K.T. (2022) Ultrasonic�assisted molten salt hydrates pretreated Eucheuma cottonii residues as a greener precursor for third-generation L-lactic acid production. Bioresource Technology, 364. ISSN 09608524 relation: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85140083701&doi=10.1016%2fj.biortech.2022.128136&partnerID=40&md5=090c7386744deb504f9d2c0248ea5681 relation: 10.1016/j.biortech.2022.128136 identifier: 10.1016/j.biortech.2022.128136