%O cited By 0; Conference of 6th International Conference on Fundamental and Applied Sciences, ICFAS 2020 ; Conference Date: 13 July 2021 Through 15 July 2021; Conference Code:270909
%J Springer Proceedings in Complexity
%L scholars15549
%D 2021
%R 10.1007/978-981-16-4513-6₁₂
%X The complexes of β-cyclodextrin/pioglitazone and β-cyclodextrin-ionic liquid/pioglitazone were prepared by kneading method. Characterization using FT-IR, thermogravimetric analysis and NMR had proven the formation of the complexes. From 1H NMR determination, pioglitazone is proven to form hydrogen bonding and inclusion complex with native β-cyclodextrin and β-cyclodextrin-ionic liquid. The molecular docking also reveals the same interaction involved for the formation of complexes β-cyclodextrin/pioglitazone and β-cyclodextrin-ionic liquid/pioglitazone. The binding energy obtained from molecular studies for the complex of β-cyclodextrin-ionic liquid/pioglitazone is higher than the binding energy of β-cyclodextrin/pioglitazone. © 2021, The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.
%P 131-145
%T Inclusion Complexes of β-Cyclodextrin/Pioglitazone and β-Cyclodextrin-Ionic Liquid/Pioglitazone: Spectroscopic Methods Combined with Molecular Docking Studies
%A N.Y. Rahim
%A N.N. Md Zuki
%A K. Jumbri
%A S. Mohamad
%A N.S. Abdul Manan
%A N. Sidek
%A Y.H. Boon
%A M.R. Ramachandran
%I Springer Science and Business Media B.V.