@inproceedings{scholars15549, year = {2021}, doi = {10.1007/978-981-16-4513-6{$_1$}{$_2$}}, note = {cited By 0; Conference of 6th International Conference on Fundamental and Applied Sciences, ICFAS 2020 ; Conference Date: 13 July 2021 Through 15 July 2021; Conference Code:270909}, pages = {131--145}, publisher = {Springer Science and Business Media B.V.}, journal = {Springer Proceedings in Complexity}, title = {Inclusion Complexes of {\^I}2-Cyclodextrin/Pioglitazone and {\^I}2-Cyclodextrin-Ionic Liquid/Pioglitazone: Spectroscopic Methods Combined with Molecular Docking Studies}, isbn = {9789811645129}, issn = {22138684}, author = {Rahim, N. Y. and Md Zuki, N. N. and Jumbri, K. and Mohamad, S. and Abdul Manan, N. S. and Sidek, N. and Boon, Y. H. and Ramachandran, M. R.}, abstract = {The complexes of {\^I}2-cyclodextrin/pioglitazone and {\^I}2-cyclodextrin-ionic liquid/pioglitazone were prepared by kneading method. Characterization using FT-IR, thermogravimetric analysis and NMR had proven the formation of the complexes. From 1H NMR determination, pioglitazone is proven to form hydrogen bonding and inclusion complex with native {\^I}2-cyclodextrin and {\^I}2-cyclodextrin-ionic liquid. The molecular docking also reveals the same interaction involved for the formation of complexes {\^I}2-cyclodextrin/pioglitazone and {\^I}2-cyclodextrin-ionic liquid/pioglitazone. The binding energy obtained from molecular studies for the complex of {\^I}2-cyclodextrin-ionic liquid/pioglitazone is higher than the binding energy of {\^I}2-cyclodextrin/pioglitazone. {\^A}{\copyright} 2021, The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85123292787&doi=10.1007\%2f978-981-16-4513-6\%5f12&partnerID=40&md5=9bd6713074d237de4fd0d25a45778084} }