eprintid: 14829
rev_number: 2
eprint_status: archive
userid: 1
dir: disk0/00/01/48/29
datestamp: 2023-11-10 03:29:25
lastmod: 2023-11-10 03:29:25
status_changed: 2023-11-10 01:57:55
type: article
metadata_visibility: show
creators_name: Ashraf, A.
creators_name: Liu, G.
creators_name: Yousaf, B.
creators_name: Arif, M.
creators_name: Ahmed, R.
creators_name: Irshad, S.
creators_name: Cheema, A.I.
creators_name: Rashid, A.
creators_name: Gulzaman, H.
title: Recent trends in advanced oxidation process-based degradation of erythromycin: Pollution status, eco-toxicity and degradation mechanism in aquatic ecosystems
ispublished: pub
keywords: Antibiotics; Aquatic organisms; Degradation; Oxidation; Pollution; Toxicity; Water treatment, Advanced Oxidation Processes; Aquatic environments; Conventional water treatment; Degradation mechanism; Macrolide antibiotics; Oxidation potentials; Potential threats; Protein inhibition, Aquatic ecosystems, erythromycin; holmium; oxygen; ozone; sulfate; antiinfective agent; erythromycin, antibiotics; aquatic ecosystem; aquatic organism; degradation; drug; ecotoxicology; oxidation; ozonation; photochemistry; sewage outfall; sewage treatment; sulfate, aquatic environment; concentration (parameter); controlled study; drug degradation; drug structure; ecotoxicology; environmental factor; environmental impact; genetic resistance; nonhuman; oxidation; ozonation; photocatalysis; priority journal; Review; sewage treatment plant; waste water management; water pollution; analysis; ecosystem; oxidation reduction reaction; toxicity; water management; water pollutant, Anti-Bacterial Agents; Ecosystem; Erythromycin; Oxidation-Reduction; Water Pollutants, Chemical; Water Purification
note: cited By 30
abstract: Wide spread documentation of antibiotic pollution is becoming a threat to aquatic environment. Erythromycin (ERY), a macrolide belonging antibiotic is at the top of this list with its concentrations ranging between ng/L to a few μg/L in various global waterbodies giving rise to ERY-resistance genes (ERY-RGs) and ERY- resistance bacteria (ERY-RBs) posing serious threat to the aquatic organisms. ERY seems resistant to various conventional water treatments, remained intact and even increased in terms of mass loads after treatment. Enhanced oxidation potential, wide pH range, elevated selectivity, adaptability and greater efficiency makes advance oxidation processes (AOPs) top priority for degrading pollutants with aromatic rings and unsaturated bonds like ERY. In this manuscript, recent developments in AOPs for ERY degradation are reported along with the factors that affect the degradation mechanism. ERY, marked as a risk prioritized macrolide antibiotic by 2015 released European Union watch list, most probably due to its protein inhibition capability considered third most widely used antibiotic. The current review provides a complete ERY overview including the environmental entry sources, concentration in global waters, ERY status in STPs, as well as factors affecting their functionality. Along with that this study presents complete outlook regarding ERY-RGs and provides an in depth detail regarding ERY's potential threats to aquatic biota. This study helps in figuring out the best possible strategy to tackle antibiotic pollution keeping ERY as a model antibiotic because of extreme toxicity records. © 2021
date: 2021
publisher: Elsevier B.V.
official_url: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100722369&doi=10.1016%2fj.scitotenv.2021.145389&partnerID=40&md5=b559de6dd81f149aa736ab6655868430
id_number: 10.1016/j.scitotenv.2021.145389
full_text_status: none
publication: Science of the Total Environment
volume: 772
refereed: TRUE
issn: 00489697
citation:   Ashraf, A. and Liu, G. and Yousaf, B. and Arif, M. and Ahmed, R. and Irshad, S. and Cheema, A.I. and Rashid, A. and Gulzaman, H.  (2021) Recent trends in advanced oxidation process-based degradation of erythromycin: Pollution status, eco-toxicity and degradation mechanism in aquatic ecosystems.  Science of the Total Environment, 772.   ISSN 00489697