@inproceedings{scholars14742, doi = {10.1051/e3sconf/202128702012}, year = {2021}, volume = {287}, note = {cited By 0; Conference of 2021 International Conference on Process Engineering and Advanced Materials, ICPEAM2020 ; Conference Date: 13 July 2021 Through 15 July 2021; Conference Code:185461}, title = {Influence of supercritical CO2 flowrate in one-pot supercritical fluid extraction of Carica papaya linn. leaves: A broken-intact-cell approach}, journal = {E3S Web of Conferences}, publisher = {EDP Sciences}, issn = {25550403}, author = {Chai, Y. H. and Yusup, S. and Seer, Q. H. and Ruslan, M. S. H. and Chin, B. L. F.}, abstract = {The presence of rich phytochemicals in Carica papaya linn. leaves are potentially beneficial in pharmaceutical, nutraceutical and food industries. This work aims to investigate the roles of solvent flowrate for the predictive behaviour of supercritical fluid extraction of essential oil-rich extracts by broken-intact-cell modelling approach. Through kinetic model fitting of experimental data, the adjustable parameters namely G, {\"I}?k, Z and Y were determined through error minimization procedure. From the cumulative extraction curve at solvent rate from 4-8 mL/min, the values of mass transfer coefficients were in the range of 4.40 x 10-5 m2/s - 19.92 x 10-5 m2/s with an overall relative 8.67 AARD. The grinding index and end of fast extraction time period was within the range of 0.144-0.258 and 30.38-91.17 min respectively. The role of solvent flowrate played an influential role in the extraction of papaya leaves extract. {\^A}{\copyright} The Authors, published by EDP Sciences. This is an open access article distributed under the terms of the Creative Commons Attribution License 4.0 (http://creativecommons.org/licenses/by/4.0/)}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85145453749&doi=10.1051\%2fe3sconf\%2f202128702012&partnerID=40&md5=e6b0e86066f5fd4447b94224dd372a62} }