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primary topic: Synthesis of Ethyl 3-Methyl-4,5-dioxo-1,2-diphenylpyrrolidine-3-carboxylate Analogues Using Green and Expeditious Grinding Method

Synthesis of Ethyl 3-Methyl-4,5-dioxo-1,2-diphenylpyrrolidine-3-carboxylate Analogues Using Green and Expeditious Grinding Method
type: AcademicArticle
type: Article
abstract: Abstract: A specific efficient method of synthesis of biologically active analogues of the title compound from acetylene dicarboxylate, aniline and various aromatic aldehydes catalyzed by citric acid by one-pot mortar-pestle grinding is described. The short time synthesis is characterized by high yields and comparable with the similar mechano-chemical process of planetary ball-milling. Easy isolation of the products without involving separation methods makes this green synthesis to be cost-efficient. © 2021, Pleiades Publishing, Ltd.
date: 2021
volume: 91
issue: 11
is part of: Russian Journal of General Chemistry
status: peerReviewed
status: published
author list: authors
type: EPrint
type: ArticleEPrint
is part of: repository

Pleiades journals
type: Organization

Russian Journal of General Chemistry
type: Collection
issn: 10703632

M.F. Mohammat
type: Person
given name: M.F.
family name: Mohammat

S.N.M. Salleh
type: Person
given name: S.N.M.
family name: Salleh

F.N.A.A. Rashid
type: Person
given name: F.N.A.A.
family name: Rashid

A.S. Hamzah
type: Person
given name: A.S.
family name: Hamzah

S.A. Johari
type: Person
given name: S.A.
family name: Johari

U. Safyudin
type: Person
given name: U.
family name: Safyudin

Z. Shaameri
type: Person
given name: Z.
family name: Shaameri

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primary topic: Synthesis of Ethyl 3-Methyl-4,5-dioxo-1,2-diphenylpyrrolidine-3-carboxylate Analogues Using Green and Expeditious Grinding Method