eprintid: 14216
rev_number: 2
eprint_status: archive
userid: 1
dir: disk0/00/01/42/16
datestamp: 2023-11-10 03:28:47
lastmod: 2023-11-10 03:28:47
status_changed: 2023-11-10 01:56:20
type: article
metadata_visibility: show
creators_name: Loganathan, K.
creators_name: Lv, J.
creators_name: Cropley, V.
creators_name: Zalesky, A.
creators_name: Ho, E.T.W.
title: Valuation system connectivity is correlated with poly-drug use in young adults
ispublished: pub
keywords: alcohol; cannabis; central stimulant agent; cocaine; illicit drug; opiate; psychedelic agent; sedative agent; drug, adult; Article; cannabis use; connectome; controlled study; drug use; evidence based practice; executive function; female; functional connectivity; functional magnetic resonance imaging; head movement; human; major clinical study; male; medical information system; multiple drug abuse; neuroscience; population; signal noise ratio; substance use; tobacco use; valuation control complex; valuation system connectivity; young adult; brain; drug dependence; nuclear magnetic resonance imaging, Brain; Executive Function; Humans; Magnetic Resonance Imaging; Pharmaceutical Preparations; Substance-Related Disorders; Young Adult
note: cited By 2
abstract: Poly-drug consumption contributes to fatal overdose in more than half of all poly-drug users. Analyzing decision-making networks may give insight into the motivations behind poly-drug use. We correlated average functional connectivity of the valuation system (VS), executive control system (ECS) and valuation-control complex (VCC) in a large population sample (n = 992) with drug use behaviour. VS connectivity is correlated with sedative use, ECS connectivity is separately correlated with hallucinogens and opiates. Network connectivity is also correlated with drug use via two-way interactions with other substances including alcohol and tobacco. These preliminary findings can contribute to our understanding of the common combinations of substance co-use and associated neural patterns. © 2021 Elsevier B.V. and Japan Neuroscience Society
date: 2021
publisher: Elsevier Ireland Ltd
official_url: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85109778725&doi=10.1016%2fj.neures.2021.06.006&partnerID=40&md5=e0fa4b716e6e89292c36f2cf2345b246
id_number: 10.1016/j.neures.2021.06.006
full_text_status: none
publication: Neuroscience Research
volume: 173
pagerange: 114-120
refereed: TRUE
issn: 01680102
citation:   Loganathan, K. and Lv, J. and Cropley, V. and Zalesky, A. and Ho, E.T.W.  (2021) Valuation system connectivity is correlated with poly-drug use in young adults.  Neuroscience Research, 173.  pp. 114-120.  ISSN 01680102