TY  - JOUR
SN  - 01680102
JF  - Neuroscience Research
N1  - cited By 2
TI  - Valuation system connectivity is correlated with poly-drug use in young adults
N2  - Poly-drug consumption contributes to fatal overdose in more than half of all poly-drug users. Analyzing decision-making networks may give insight into the motivations behind poly-drug use. We correlated average functional connectivity of the valuation system (VS), executive control system (ECS) and valuation-control complex (VCC) in a large population sample (n = 992) with drug use behaviour. VS connectivity is correlated with sedative use, ECS connectivity is separately correlated with hallucinogens and opiates. Network connectivity is also correlated with drug use via two-way interactions with other substances including alcohol and tobacco. These preliminary findings can contribute to our understanding of the common combinations of substance co-use and associated neural patterns. © 2021 Elsevier B.V. and Japan Neuroscience Society
ID  - scholars14216
EP  - 120
UR  - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85109778725&doi=10.1016%2fj.neures.2021.06.006&partnerID=40&md5=e0fa4b716e6e89292c36f2cf2345b246
KW  - alcohol; cannabis; central stimulant agent; cocaine; illicit drug; opiate; psychedelic agent; sedative agent; drug
KW  -  adult; Article; cannabis use; connectome; controlled study; drug use; evidence based practice; executive function; female; functional connectivity; functional magnetic resonance imaging; head movement; human; major clinical study; male; medical information system; multiple drug abuse; neuroscience; population; signal noise ratio; substance use; tobacco use; valuation control complex; valuation system connectivity; young adult; brain; drug dependence; nuclear magnetic resonance imaging
KW  -  Brain; Executive Function; Humans; Magnetic Resonance Imaging; Pharmaceutical Preparations; Substance-Related Disorders; Young Adult
PB  - Elsevier Ireland Ltd
A1  - Loganathan, K.
A1  - Lv, J.
A1  - Cropley, V.
A1  - Zalesky, A.
A1  - Ho, E.T.W.
SP  - 114
AV  - none
Y1  - 2021///
VL  - 173
ER  -