<> "The repository administrator has not yet configured an RDF license."^^ . <> . . . "1,1'-Carbonyldiimidazole-copper nanoflower enhanced collapsible laser scribed graphene engraved microgap capacitive aptasensor for the detection of milk allergen"^^ . "The bovine milk allergenic protein, �β-lactoglobulin� is one of the leading causes of milk allergic reaction. In this research, a novel label-free non-faradaic capacitive aptasensor was designed to detect β-lactoglobulin using a Laser Scribed Graphene (LSG) electrode. The graphene was directly engraved into a microgapped (~ 95 µm) capacitor-electrode pattern on a flexible polyimide (PI) film via a simple one-step CO2 laser irradiation. The novel hybrid nanoflower (NF) was synthesized using 1,1�-carbonyldiimidazole (CDI) as the organic molecule and copper (Cu) as the inorganic molecule via one-pot biomineralization by tuning the reaction time and concentration. NF was fixed on the pre-modified PI film at the triangular junction of the LSG microgap specifically for bio-capturing β-lactoglobulin. The fine-tuned CDI-Cu NF revealed the flower-like structures was viewed through field emission scanning electron microscopy. Fourier-transform infrared spectroscopy showed the interactions with PI film, CDI-Cu NF, oligoaptamer and β-lactoglobulin. The non-faradaic sensing of milk allergen β-lactoglobulin corresponds to a higher loading of oligoaptamer on 3D-structured CDI-Cu NF, with a linear range detection from 1 ag/ml to 100 fg/ml and attomolar (1 ag/ml) detection limit (S/N = 3:1). This novel CDI-Cu NF/LSG microgap aptasensor has a great potential for the detection of milk allergen with high-specificity and sensitivity. © 2021, The Author(s)."^^ . "2021" . . "11" . "1" . . "Nature Research"^^ . . . "Scientific Reports"^^ . . . "20452322" . . . . . . . . . . . . . . . . . . . . . . "M."^^ . "Ovinis"^^ . "M. Ovinis"^^ . . "V."^^ . "Perumal"^^ . "V. Perumal"^^ . . "S.C.B."^^ . "Gopinath"^^ . "S.C.B. Gopinath"^^ . . "I.G."^^ . "Subramani"^^ . "I.G. Subramani"^^ . . "L.L."^^ . "Sze"^^ . "L.L. Sze"^^ . . "N.M."^^ . "Mohamed"^^ . "N.M. Mohamed"^^ . . . . . "HTML Summary of #14189 \n\n1,1'-Carbonyldiimidazole-copper nanoflower enhanced collapsible laser scribed graphene engraved microgap capacitive aptasensor for the detection of milk allergen\n\n" . "text/html" . .