%0 Journal Article
%@ 13590294
%A Moshikur, R.M.
%A Ali, M.K.
%A Moniruzzaman, M.
%A Goto, M.
%D 2021
%F scholars:14188
%I Elsevier Ltd
%J Current Opinion in Colloid and Interface Science
%K Biocompatibility; Controlled drug delivery; Ionic liquids; Ions; Liposomes; Micelles; Self assembly; Surface active agents; Targeted drug delivery, Assembly systems; Conventional surfactants; Diverse range; Drug formulations; Ion pairs; Pharmaceutical industry; Self-assembled systems; Surface active ionic liquids; Tunables; Vesicle, Microemulsions, ionic liquid; liposome; self assembled nanoparticle; surfactant, drug delivery system; drug formulation; human; micelle; micellization; nanopharmaceutics; oral drug administration; Review; surface property; transdermal drug administration
%R 10.1016/j.cocis.2021.101515
%T Recent advances in surface-active ionic liquid-assisted self-assembly systems for drug delivery
%U https://khub.utp.edu.my/scholars/14188/
%V 56
%X Surface-active ionic liquids (SAILs) are receiving growing interest as environmentally friendly designer surfactants for various applications, including drug formulation and delivery. The use of SAILs in the pharmaceutical industry has the potential to address the challenges associated with conventional surfactants. The tunable formation of complementary ion pairs from a diverse range of ions enables the task-specific optimization of SAILs. SAILs comprising second and third-generation cations and anions have been used to design biocompatible self-assembled systems including micelles, microemulsions, vesicles, liposomes, and nanoparticles for drug delivery carriers. Compared with conventional surfactant-based carriers, SAIL-based systems offer better pharmacokinetic and pharmacodynamic properties. This mini-review highlights recent findings on the formation of ionic liquid-based self-assembled systems and their potential applications in drug delivery. © 2021 Elsevier Ltd
%Z cited By 23