eprintid: 13718 rev_number: 2 eprint_status: archive userid: 1 dir: disk0/00/01/37/18 datestamp: 2023-11-10 03:28:17 lastmod: 2023-11-10 03:28:17 status_changed: 2023-11-10 01:51:50 type: article metadata_visibility: show creators_name: Chai, Y.H. creators_name: Yusup, S. creators_name: Ruslan, M.S.H. title: Review of bioactive compounds extracted from carica papaya linn ispublished: pub keywords: alkaloid derivative; Carica papaya extract; flavonoid; glycoside; organic solvent; saponin derivative; tannin derivative; volatile organic compound, benchmarking; evaluation study; extraction; extraction time; freeze drying; fruit pulp; green chemistry; high temperature; microwave assisted extraction; nonhuman; papaya; particle size; phytochemistry; plant leaf; plant root; plant seed; priority journal; scale up; Short Survey; Soxhlet extraction; supercritical fluid extraction; surface area; systematic review; thin layer chromatography; ultrasound assisted extraction; Web of Science note: cited By 4 abstract: The presence of phytochemical constituents, such as alkaloids, flavonoids, polyphenols, fatty acids, etc., within various parts of Carica papaya is highly valuable for various health and medicinal benefits. This paper aimed to review various sample preparation and extraction methods, including conventional extraction and greener extraction methods of phytochemical compounds from Carica papaya. In this review, the methodology used was based on comprehensive data searched from the Web of Science for literature review and technology benchmarking. An in-depth discussion, including advantages and drawbacks, of each sample and extraction methods of Carica papaya Linn. are presented and outlined. Furthermore, key solutions were proposed to overcome issues faced in conventional extraction methods and the challenges encountered in larger extraction scale ratios were also presented to complement the movement towards more sustainable and greener extraction processes. © 2020 Bentham Science Publishers. date: 2020 publisher: Bentham Science Publishers official_url: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85093918497&doi=10.2174%2f1573401316999200727142506&partnerID=40&md5=21eac71b642f7f7b0a08b40a59ee0a1c id_number: 10.2174/1573401316999200727142506 full_text_status: none publication: Current Nutrition and Food Science volume: 16 number: 9 pagerange: 1287-1298 refereed: TRUE issn: 15734013 citation: Chai, Y.H. and Yusup, S. and Ruslan, M.S.H. (2020) Review of bioactive compounds extracted from carica papaya linn. Current Nutrition and Food Science, 16 (9). pp. 1287-1298. ISSN 15734013