%K alkaloid derivative; Carica papaya extract; flavonoid; glycoside; organic solvent; saponin derivative; tannin derivative; volatile organic compound, benchmarking; evaluation study; extraction; extraction time; freeze drying; fruit pulp; green chemistry; high temperature; microwave assisted extraction; nonhuman; papaya; particle size; phytochemistry; plant leaf; plant root; plant seed; priority journal; scale up; Short Survey; Soxhlet extraction; supercritical fluid extraction; surface area; systematic review; thin layer chromatography; ultrasound assisted extraction; Web of Science
%X The presence of phytochemical constituents, such as alkaloids, flavonoids, polyphenols, fatty acids, etc., within various parts of Carica papaya is highly valuable for various health and medicinal benefits. This paper aimed to review various sample preparation and extraction methods, including conventional extraction and greener extraction methods of phytochemical compounds from Carica papaya. In this review, the methodology used was based on comprehensive data searched from the Web of Science for literature review and technology benchmarking. An in-depth discussion, including advantages and drawbacks, of each sample and extraction methods of Carica papaya Linn. are presented and outlined. Furthermore, key solutions were proposed to overcome issues faced in conventional extraction methods and the challenges encountered in larger extraction scale ratios were also presented to complement the movement towards more sustainable and greener extraction processes. © 2020 Bentham Science Publishers.
%O cited By 4
%L scholars13718
%J Current Nutrition and Food Science
%D 2020
%R 10.2174/1573401316999200727142506
%N 9
%T Review of bioactive compounds extracted from carica papaya linn
%V 16
%I Bentham Science Publishers
%A Y.H. Chai
%A S. Yusup
%A M.S.H. Ruslan
%P 1287-1298