%N 1
%R 10.1021/acs.jced.9b00654
%D 2020
%O cited By 7
%V 65
%T Synthesis, Characterization, and Antimicrobial Toxicity Study of Dicyanamide-Based Ionic Liquids and Their Application to Liquid-Liquid Extraction
%K Atmospheric pressure; Ethylbenzene; Ionic liquids; Microorganisms; Ternary systems; Toxicity, Anti-microbial activity; Bacterial pathogens; Distribution ratio; Effective concentration; Equilibrium data; Ionic liquid (ils); Liquid-liquid extraction; Nonrandom two-liquid model, Solvent extraction
%X Four different dicyanamide-based ionic liquids (ILs), CnmpyDCA (n = 4, 6, 8, and 10), were synthesized, characterized, and used to separate ethylbenzene from n-octane. Equilibrium data for the corresponding ternary systems were measured at 313.15 K under atmospheric pressure. A higher selectivity is observed for lower aromatic concentrations in the feed (20% max); this is a key factor in selecting a suitable IL. The distribution ratio and selectivity obtained in this work are comparable to those of commercial solvents. The nonrandom two-liquid model (NRTL) was successfully used to correlate the experimental tie-lines and to calculate the phase compositions of the ternary systems. Moreover, the antimicrobial activities of the ILs were evaluated by examining their 50% effective concentrations (EC50) using the standard microbroth dilution test against four human bacterial pathogens. 1-Butyl 3-methylpyridinium dicyanamide C4mpyDCA was found as the most suitable IL among those investigated because of its low toxicity with EC50 values between 41.35 and 58.08 mmol·L-1 and its performance in liquid-liquid extraction for the ethylbenzene/n-octane mixture. Copyright © 2019 American Chemical Society.
%I American Chemical Society
%L scholars13548
%P 34-42
%A L. El Blidi
%A J. Saleh
%A O. Ben Ghanem
%A M. El-Harbawi
%A J.-M. Lévêque
%A M.K. Hadj-Kali
%J Journal of Chemical and Engineering Data