TY - JOUR TI - Space-time clustering characteristics of tuberculosis in Khyber Pakhtunkhwa Province, Pakistan, 2015â??2019 ID - scholars13475 KW - cluster analysis; detection method; health impact; health risk; public health; spatial analysis; tuberculosis KW - adult; article; climate; cluster analysis; controlled study; female; human; major clinical study; male; Pakistan; spatiotemporal analysis; tuberculosis control; Pakistan; rural population; spatiotemporal analysis; tuberculosis KW - Khyber-Pakhtunkhwa; Pakistan KW - Climate; Humans; Pakistan; Rural Population; Space-Time Clustering; Tuberculosis IS - 4 N2 - The number of tuberculosis (TB) cases in Pakistan ranks fifth in the world. The National TB Control Program (NTP) has recently reported more than 462,920 TB patients in Khyber Pakhtunkhwa province, Pakistan from 2002 to 2017. This study aims to identify spatial and space-time clusters of TB cases in Khyber Pakhtunkhwa province Pakistan during 2015â??2019 to design effective interventions. The spatial and spaceâ??time cluster analyses were conducted at the district-level based on the reported TB cases from January 2015 to April 2019 using spaceâ??time scan statistics (SaTScan). The most likely spatial and spaceâ??time clusters were detected in the northern rural part of the province. Additionally, two districts in the west were detected as the secondary spaceâ??time clusters. The most likely spaceâ??time cluster shows a tendency of spread toward the neighboring districts in the central part, and the most likely spatial cluster shows a tendency of spread toward the neighboring districts in the south. Most of the spaceâ??time clusters were detected at the start of the study period 2015â??2016. The potential TB clusters in the remote rural part might be associated to the dryâ??cool climate and lack of access to the healthcare centers in the remote areas. © 2020 by the authors. Licensee MDPI, Basel, Switzerland. N1 - cited By 5 AV - none VL - 17 JF - International Journal of Environmental Research and Public Health A1 - Ullah, S. A1 - Daud, H. A1 - Dass, S.C. A1 - Fanaee-t, H. A1 - Kausarian, H. A1 - Khalil, A. UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85079833294&doi=10.3390%2fijerph17041413&partnerID=40&md5=8f08cf6a8eaca1cadeced1e211d46d1c PB - MDPI SN - 16617827 Y1 - 2020/// ER -