%D 2020 %R 10.1016/j.bspc.2019.101692 %O cited By 18 %L scholars13439 %J Biomedical Signal Processing and Control %X Online detection and removal of eye blink (EB) artifacts from electroencephalogram (EEG) would be very useful in medical diagnosis and brain computer interface (BCI). In this work, approaches that combine unsupervised eyeblink artifact detection with empirical mode decomposition (EMD), and canonical correlation analysis (CCA), are proposed to automatically identify eyeblink artifacts and remove them in an online manner. First eyeblink artifact regions are automatically identified and an eyeblink artifact template is extracted via EMD, which incorporates an alternate interpolation technique, the Akima spline interpolation. The removal of eyeblink artifact components relies on the elimination of EEG canonical components obtained through CCA, based on cross correlation with the extracted eyeblink artifact template. The proposed algorithm is evaluated and analyzed with respect to its ability in removing eyeblink artifacts and retaining neural information of the EEG signals. Analysis proved that the proposed algorithm, FastEMD�CCA, is efficacious in eyeblink artifact removal with an average accuracy, sensitivity, specificity and error rate of 97.9, 97.65, 99.22 and 2.1 respectively. The algorithm is able to clean and remove eyeblink artifacts from a 14-channel EEG of length 1 s, at an average time of 63 ms. This makes it a feasible solution for applications requiring online removal of eyeblink artifacts. © 2019 Elsevier Ltd %K Brain computer interface; Correlation methods; Interpolation; Signal processing, Canonical correlation analysis; Cross correlations; Electro-encephalogram (EEG); Empirical Mode Decomposition; Eye-blink artifact removals; Eye-blink artifacts; Interpolation techniques; Spline interpolation, Electroencephalography, algorithm; article; artifact; controlled study; correlation analysis; cross correlation; diagnostic test accuracy study; electroencephalogram; empirical mode decomposition; sensitivity and specificity %T FastEMD�CCA algorithm for unsupervised and fast removal of eyeblink artifacts from electroencephalogram %I Elsevier Ltd %V 57 %A A. Egambaram %A N. Badruddin %A V.S. Asirvadam %A T. Begum %A E. Fauvet %A C. Stolz