TY - JOUR AV - none N1 - cited By 15 TI - Supercritical fluid extraction and solubilization of Carica papaya linn. leaves in ternary system with CO2 + ethanol solvents SP - 31 PB - Institution of Chemical Engineers SN - 02638762 EP - 42 N2 - The supercritical fluid extraction of Carica papaya linn. leaves in the presence of CO2 solvent and ethanol modifier was carried out with respect to four operating parameters, namely temperature (40â??60 °C), pressure (18â??30 MPa), solvent flow rate (3â??6 mL/min) and co-solvent ratio (3 â?? 5 vol), for the maximization of global extract yield of Carica papaya linn. leaves. The optimized parameters obtained are as follows: temperature of 57.47 °C, pressure of 26.62 MPa, solvent flow rate of 5.43 mL/min and co-solvent ratio of 4.98 with a predicted global extract yield of 0.0806 g. Five density-based solubility models, namely Chrastil, Bian et al., Bartle et al., Sparks et al. and Méndez-Santiago and Teja models were correlated against experimental solubility data. The Méndez-Santiago and Teja model were found to be more accurate with AARD of 1.36 and R2 value of 0.873 due to the non-linearity extraction profiles of papaya leaves. © 2020 ID - scholars13298 KW - Carbon dioxide; Effluent treatment; Ethanol; Solubility; Supercritical fluid extraction; Supercritical fluids KW - Carica papaya; Experimental solubility datum; Extract yields; Operating parameters; Optimized parameter; Response surface methodology; Solubility models; Solvent flow rate KW - Organic solvents Y1 - 2020/// A1 - Chai, Y.H. A1 - Yusup, S. A1 - Ruslan, M.S.H. A1 - Chin, B.L.F. JF - Chemical Engineering Research and Design UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85078858842&doi=10.1016%2fj.cherd.2020.01.025&partnerID=40&md5=3d572fccd04ef5ac07c2635311c3069d VL - 156 ER -