eprintid: 13108
rev_number: 2
eprint_status: archive
userid: 1
dir: disk0/00/01/31/08
datestamp: 2023-11-10 03:27:40
lastmod: 2023-11-10 03:27:40
status_changed: 2023-11-10 01:50:21
type: article
metadata_visibility: show
creators_name: Gopinath, S.C.B.
creators_name: Perumal, V.
creators_name: Xuan, S.
title: MicroRNA-155 complementation on a chemically functionalized dual electrode surface for determining breast cancer
ispublished: pub
keywords: ethanolamine; microRNA 155; streptavidin, Article; breast cancer; cancer diagnosis; cancer growth; chemical interaction; female; gene expression; gene identification; gene targeting; genetic complementation; human; limit of detection; priority journal; RNA sequence
note: cited By 4
abstract: This study correlated and quantified the expression of microRNA-155 with breast cancer to determine breast cancer progression. The target microRNA-155 sequence was identified by complementation on a capture-probe sequence-immobilized interdigitated dual electrode surface. The sensitivity was found to be 1 fM, and the limit of detection fell between 1 and 10 fM. The specific sequence selectivity with single mismatches, triple mismatches, and noncomplementary bases failed to complement the capture-probe sequence. The obtained results demonstrate the selective determination of the microRNA-155 sequence and can help to diagnose breast cancer. © 2020, King Abdulaziz City for Science and Technology.
date: 2020
publisher: Springer
official_url: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85085604630&doi=10.1007%2fs13205-020-02261-x&partnerID=40&md5=abfa178c752b33bddc68eec5a65ac3b6
id_number: 10.1007/s13205-020-02261-x
full_text_status: none
publication: 3 Biotech
volume: 10
number: 6
refereed: TRUE
issn: 2190572X
citation:   Gopinath, S.C.B. and Perumal, V. and Xuan, S.  (2020) MicroRNA-155 complementation on a chemically functionalized dual electrode surface for determining breast cancer.  3 Biotech, 10 (6).   ISSN 2190572X