%I Springer
%V 10
%A S.C.B. Gopinath
%A V. Perumal
%A S. Xuan
%T MicroRNA-155 complementation on a chemically functionalized dual electrode surface for determining breast cancer
%X This study correlated and quantified the expression of microRNA-155 with breast cancer to determine breast cancer progression. The target microRNA-155 sequence was identified by complementation on a capture-probe sequence-immobilized interdigitated dual electrode surface. The sensitivity was found to be 1 fM, and the limit of detection fell between 1 and 10 fM. The specific sequence selectivity with single mismatches, triple mismatches, and noncomplementary bases failed to complement the capture-probe sequence. The obtained results demonstrate the selective determination of the microRNA-155 sequence and can help to diagnose breast cancer. © 2020, King Abdulaziz City for Science and Technology.
%K ethanolamine; microRNA 155; streptavidin, Article; breast cancer; cancer diagnosis; cancer growth; chemical interaction; female; gene expression; gene identification; gene targeting; genetic complementation; human; limit of detection; priority journal; RNA sequence
%J 3 Biotech
%L scholars13108
%O cited By 4
%R 10.1007/s13205-020-02261-x
%N 6
%D 2020