@article{scholars13108, year = {2020}, publisher = {Springer}, journal = {3 Biotech}, doi = {10.1007/s13205-020-02261-x}, volume = {10}, note = {cited By 4}, number = {6}, title = {MicroRNA-155 complementation on a chemically functionalized dual electrode surface for determining breast cancer}, keywords = {ethanolamine; microRNA 155; streptavidin, Article; breast cancer; cancer diagnosis; cancer growth; chemical interaction; female; gene expression; gene identification; gene targeting; genetic complementation; human; limit of detection; priority journal; RNA sequence}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85085604630&doi=10.1007\%2fs13205-020-02261-x&partnerID=40&md5=abfa178c752b33bddc68eec5a65ac3b6}, abstract = {This study correlated and quantified the expression of microRNA-155 with breast cancer to determine breast cancer progression. The target microRNA-155 sequence was identified by complementation on a capture-probe sequence-immobilized interdigitated dual electrode surface. The sensitivity was found to be 1 fM, and the limit of detection fell between 1 and 10 fM. The specific sequence selectivity with single mismatches, triple mismatches, and noncomplementary bases failed to complement the capture-probe sequence. The obtained results demonstrate the selective determination of the microRNA-155 sequence and can help to diagnose breast cancer. {\^A}{\copyright} 2020, King Abdulaziz City for Science and Technology.}, issn = {2190572X}, author = {Gopinath, S. C. B. and Perumal, V. and Xuan, S.} }