TY - JOUR N2 - This work studied the bioremediation of weathered crude oil (WCO) in coastal sediment samples using central composite face centered design (CCFD) under response surface methodology (RSM). Initial oil concentration, biomass, nitrogen and phosphorus concentrations were used as independent variables (factors) and oil removal as dependent variable (response) in a 60 days trial. A statistically significant model for WCO removal was obtained. The coefficient of determination (R2 = 0.9732) and probability value (P < 0.0001) demonstrated significance for the regression model. Numerical optimization based on desirability function were carried out for initial oil concentration of 2, 16 and 30 g per kg sediment and 83.13, 78.06 and 69.92 per cent removal were observed respectively, compare to 77.13, 74.17 and 69.87 per cent removal for un-optimized results. © 2009 Elsevier Ltd. All rights reserved. IS - 3 KW - Central composite; Coastal sediments; Coefficient of determination; Dependent variables; Desirability function; Independent variables; Nitrogen nutrient; Numerical optimizations; Oil concentration; Oil removal; Phosphorus concentration; Regression model; Response Surface Methodology; Statistical experiments; Statistically significant models; Weathered crude oil KW - Biodegradation; Biomass; Bioremediation; Biotechnology; Crude petroleum; Nitrogen; Nutrients; Optimization; Phosphorus; Pollution; Probability density function; Regression analysis; Sedimentology KW - Nitrogen removal KW - nitrogen; petroleum; phosphorus KW - biodegradation; bioremediation; coastal sediment; concentration (composition); crude oil; experimental design; nitrogen; numerical model; optimization; phosphorus; pollutant removal; sediment pollution KW - article; biomass; bioremediation; concentration (parameters); controlled study; Malaysia; mathematical analysis; priority journal; probability; process optimization; response surface method; seashore; sediment; statistical analysis; statistical significance; waste component removal KW - Biodegradation KW - Environmental; Biomass; Geologic Sediments; Industrial Waste; Models KW - Statistical; Nitrogen; Oils; Petroleum; Phosphorus; Regression Analysis; Reproducibility of Results; Software; Temperature; Time Factors; Waste Disposal KW - Fluid; Water Pollutants KW - Chemical ID - scholars1310 Y1 - 2010/// UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-70450165321&doi=10.1016%2fj.biortech.2009.09.013&partnerID=40&md5=42694ae36931c9c8d53fbe6d0a8e018d JF - Bioresource Technology A1 - Mohajeri, L. A1 - Aziz, H.A. A1 - Isa, M.H. A1 - Zahed, M.A. VL - 101 AV - none N1 - cited By 112 TI - A statistical experiment design approach for optimizing biodegradation of weathered crude oil in coastal sediments SP - 893 SN - 09608524 EP - 900 ER -