eprintid: 1301 rev_number: 2 eprint_status: archive userid: 1 dir: disk0/00/00/13/01 datestamp: 2023-11-09 15:49:27 lastmod: 2023-11-09 15:49:27 status_changed: 2023-11-09 15:39:26 type: article metadata_visibility: show creators_name: Shuib, A.S. creators_name: Hoskins, P.R. creators_name: Easson, W.J. title: Flow regime characterization in a diseased artery model ispublished: pub keywords: Arterial stenosis; Atherosclerosis; Axisymmetric models; Cardio-vascular disease; Contraction and expansion; Cosine functions; Diameter reduction; Flow regimes; Heart attack; Lumen reduction; Mathematical forms; Particle image velocimetries; Particle laden flows; Rate increase; Spherical particle; Stenosis artery; Turbulent regime; Vessel walls, Computer simulation; Cosine transforms; Diseases; Flow visualization; Fluids; Functions; Inlet flow; Laminar flow; Sodium chloride; Velocimeters; Velocity measurement; Walls (structural partitions), Computational fluid dynamics note: cited By 4 abstract: Cardiovascular disease mostly in the form of atherosclerosis is responsible for 30 of all world deaths amounting to 17 million people per year. Atherosclerosis is due to the formation of plaque. The fatty plaque may be at risk of rupture, leading typically to stroke and heart attack. The plaque is usually associated with a high degree of lumen reduction, called a stenosis. The initiation and progression of the disease is strongly linked to the hemodynamic environment near the vessel wall. The aim of this study is to validate the flow of blood mimic through an arterial stenosis model with computational fluid dynamics (CFD) package. In experiment, an axisymmetric model constructed consists of contraction and expansion region that follow a mathematical form of cosine function. A 30 diameter reduction was used in this study. Particle image velocimetry (PIV) was used to characterize the flow. The fluid consists of rigid spherical particles suspended in waterglycerol- NaCl mixture. The particles with 20 μm diameter were selected to follow the flow of fluid. The flow at Re=155, 270 and 390 were investigated. The experimental result is compared with FLUENT simulated flow that account for viscous laminar flow model. The results suggest that laminar flow model was sufficient to predict flow velocity at the inlet but the velocity at stenosis throat at Re =390 was overestimated. Hence, a transition to turbulent regime might have been developed at throat region as the flow rate increases. date: 2010 official_url: https://www.scopus.com/inward/record.uri?eid=2-s2.0-78651563686&partnerID=40&md5=2e39bb0086faac0561cf89655001315d full_text_status: none publication: World Academy of Science, Engineering and Technology volume: 62 pagerange: 110-114 refereed: TRUE issn: 2010376X citation: Shuib, A.S. and Hoskins, P.R. and Easson, W.J. (2010) Flow regime characterization in a diseased artery model. World Academy of Science, Engineering and Technology, 62. pp. 110-114. ISSN 2010376X