@article{scholars12913,
             doi = {10.1080/0972060X.2020.1828179},
           title = {Chemical Composition of Essential Oil of Garcinia gummi-gutta and Its Antimicrobial and Cytotoxic Activities},
           pages = {832--842},
            note = {cited By 6},
          number = {4},
         journal = {Journal of Essential Oil-Bearing Plants},
            year = {2020},
          volume = {23},
       publisher = {Har Krishan Bhalla and Sons},
        abstract = {Garcinia gummi-gutta L. or better known as Malabar tamarind, belongs to the family of Clusiaceae. The plant is widely used for folk medicine and food preparation. The present study aimed to examine the chemical composition, anti-microbial, and cytotoxic activities of essential oil extracted from the leaf of G. gummi-gutta (EOG). EOG obtained was analyzed using chromatography techniques and its antimicrobial activity and cytotoxic potential were assessed. A total of nineteen constituents were identified with both {\^I}2- caryophyllene (53.82 ) and (E)-{\^I}2-farnesene (22.62 ) predominated in the EOG. In the antimicrobial assay, the EOG exhibited a substantial effect on methicillin-resistant Staphylococcus aureus (MRSA) with MIC of 0.156 {\^I}1/4g/mL. On the other hand, in vitro 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay showed that the EOG exhibited a notable cytotoxic effect against human breast cancer MDA-MB-231 and MCF- 7/TAM(R) cells. It is worth to point out that the EOG had a high cytotoxic selectivity toward MDA-MB-231 (4.38) and MCF-7/TAM(R) (4.0) cancer cells, which indicates its potential as therapeutic agents. {\^A}{\copyright} 2020 Har Krishan Bhalla \& Sons.},
          author = {Tan, W.-N. and Tong, W.-Y. and Leong, C.-R. and Nik Mohamed Kamal, N. N. S. and Muhamad, M. and Lim, J.-W. and Khairuddean, M. and Her Man, M. B.},
            issn = {0972060X},
             url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85092239257&doi=10.1080\%2f0972060X.2020.1828179&partnerID=40&md5=c344f51d3c92694815dd613d7f6def8e}
}