relation: https://khub.utp.edu.my/scholars/12106/ title: Salicylate-based protic ionic liquids as a potential antioxidant Cecair ionik protik berasaskan salisilat berpotensi sebagai antioksida creator: Ahmad, N.A. creator: Jumbri, K. creator: Ramli, A. creator: Ghani, N. creator: Ahmad, H. description: Salicylate-based protic ionic liquids (PILs) were synthesised, characterised and assessed in this study for potential antioxidant in drug design. The synthesised PILs were known as 3-dimethylamino-1-propanol salicylate (3DMAPS) and 3-diethylamino-1-propanol salicylate (3DEAPS). Proton nuclear magnetic resonance (1HNMR), Fourier transformation infrared spectroscopy (FTIR) and thermogravimetric analysis (TGA) were used to characterise the synthesised PILs. Furthermore, the antioxidant activity of the synthesised PILs was determined using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical assay. Both 3DMAPS and 3DEAPS showed a good antioxidant activity compared to parent acid (salicylic acid) as these two compounds could scavenge 20 of DPPH free radical at a concentration of 66.76 ± 0.09 μM and 27.27 ± 0.10 μM, respectively. © 2019, Malaysian Society of Analytical Sciences. All rights reserved. publisher: Malaysian Society of Analytical Sciences date: 2019 type: Article type: PeerReviewed identifier: Ahmad, N.A. and Jumbri, K. and Ramli, A. and Ghani, N. and Ahmad, H. (2019) Salicylate-based protic ionic liquids as a potential antioxidant Cecair ionik protik berasaskan salisilat berpotensi sebagai antioksida. Malaysian Journal of Analytical Sciences, 23 (3). pp. 383-389. ISSN 13942506 relation: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85069162177&doi=10.17576%2fmjas-2019-2303-02&partnerID=40&md5=293dc5637babc082d8b1a9535360be47 relation: 10.17576/mjas-2019-2303-02 identifier: 10.17576/mjas-2019-2303-02