eprintid: 11537
rev_number: 2
eprint_status: archive
userid: 1
dir: disk0/00/01/15/37
datestamp: 2023-11-10 03:26:03
lastmod: 2023-11-10 03:26:03
status_changed: 2023-11-10 01:15:30
type: article
metadata_visibility: show
creators_name: Jajuli, M.N.
creators_name: Hussin, M.H.
creators_name: Saad, B.
creators_name: Rahim, A.A.
creators_name: Hébrant, M.
creators_name: Herzog, G.
title: Electrochemically Modulated Liquid-Liquid Extraction for Sample Enrichment
ispublished: pub
keywords: High performance liquid chromatography, Enrichment factors; Extraction conditions; Extraction efficiencies; Interfacial potential; Liquid-liquid extraction; Pharmaceutical compounds; Sample preparation methods; Tetramethylammonium, Extraction
note: cited By 11
abstract: A new sample preparation method is proposed for the extraction of pharmaceutical compounds (Metformin, Phenyl biguanide, and Phenformin) of varied hydrophilicity, dissolved in an aqueous sample. When in contact with an organic phase, an interfacial potential is imposed by the presence of an ion, tetramethylammonium (TMA+), common to each phase. The interfacial potential difference drives the transfer of ionic analytes across the interface and allows it to reach up to nearly 100 extraction efficiency and a 60-fold enrichment factor in optimized extraction conditions as determined by HPLC analysis. © 2019 American Chemical Society.
date: 2019
publisher: American Chemical Society
official_url: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85066853156&doi=10.1021%2facs.analchem.9b01674&partnerID=40&md5=d98d811bb10c0749683ae7ac34ffa277
id_number: 10.1021/acs.analchem.9b01674
full_text_status: none
publication: Analytical Chemistry
volume: 91
number: 11
pagerange: 7466-7473
refereed: TRUE
issn: 00032700
citation:   Jajuli, M.N. and Hussin, M.H. and Saad, B. and Rahim, A.A. and Hébrant, M. and Herzog, G.  (2019) Electrochemically Modulated Liquid-Liquid Extraction for Sample Enrichment.  Analytical Chemistry, 91 (11).  pp. 7466-7473.  ISSN 00032700