TY  - JOUR
VL  - 289
JF  - Bioresource Technology
A1  - Chia, S.R.
A1  - Chew, K.W.
A1  - Show, P.L.
A1  - Xia, A.
A1  - Ho, S.-H.
A1  - Lim, J.W.
UR  - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85068260797&doi=10.1016%2fj.biortech.2019.121727&partnerID=40&md5=b5abf95cbe88e7aeee2030e81c0b6e3d
PB  - Elsevier Ltd
SN  - 09608524
Y1  - 2019///
ID  - scholars11288
TI  - Spirulina platensis based biorefinery for the production of value-added products for food and pharmaceutical applications
KW  - Algae; Extraction; Microorganisms
KW  -  Downstream-processing; Liquid biphasic systems; Micro-algae; Pharmaceutical applications; Phycobiliproteins; Processing technique; Sonication treatment; Value added products
KW  -  Purification
KW  -  phycobiliprotein; phycocyanin; drug
KW  -  bioreactor; drug; food processing; irradiation; microalga; protein; purification; recovery method
KW  -  Arthrospira platensis; Article; biomass; cell disruption; downstream processing; drug industry; electromagnetic radiation; food industry; freeze thawing; irradiation; microalga; microwave cooking; microwave irradiation; microwave radiation; nonhuman; priority journal; protein isolation; protein purification; ultrasound; microalga; Spirulina
KW  -  algae; Spirulina platensis
KW  -  Biomass; Microalgae; Pharmaceutical Preparations; Phycobiliproteins; Spirulina
N2  - In this present study, microalgal phycobiliproteins were isolated and purified via potential biphasic processing technique for pharmaceutical as well as food applications. The algal pre-treatment techniques were studied to enhance the yield of microalgal phycobiliproteins from the biomass. The proposed methods were optimised to obtain the best recovery yield of phycobiliproteins that can be isolated from the biomass. The phycobiliproteins were further purified using liquid biphasic system. The results showed that microalgal phycobiliproteins of high purity and yield was achieved using sonication treatment (20 power, 50 duty cycle and 7 min of irradiation time) with the biphasic system, where the purification fold of 6.17 and recovery yield of 94.89 was achieved. This work will provide insights towards the effective downstream processing of biomolecules from microalgae. © 2019 Elsevier Ltd
N1  - cited By 34
AV  - none
ER  -