relation: https://khub.utp.edu.my/scholars/11288/ title: Spirulina platensis based biorefinery for the production of value-added products for food and pharmaceutical applications creator: Chia, S.R. creator: Chew, K.W. creator: Show, P.L. creator: Xia, A. creator: Ho, S.-H. creator: Lim, J.W. description: In this present study, microalgal phycobiliproteins were isolated and purified via potential biphasic processing technique for pharmaceutical as well as food applications. The algal pre-treatment techniques were studied to enhance the yield of microalgal phycobiliproteins from the biomass. The proposed methods were optimised to obtain the best recovery yield of phycobiliproteins that can be isolated from the biomass. The phycobiliproteins were further purified using liquid biphasic system. The results showed that microalgal phycobiliproteins of high purity and yield was achieved using sonication treatment (20 power, 50 duty cycle and 7 min of irradiation time) with the biphasic system, where the purification fold of 6.17 and recovery yield of 94.89 was achieved. This work will provide insights towards the effective downstream processing of biomolecules from microalgae. © 2019 Elsevier Ltd publisher: Elsevier Ltd date: 2019 type: Article type: PeerReviewed identifier: Chia, S.R. and Chew, K.W. and Show, P.L. and Xia, A. and Ho, S.-H. and Lim, J.W. (2019) Spirulina platensis based biorefinery for the production of value-added products for food and pharmaceutical applications. Bioresource Technology, 289. ISSN 09608524 relation: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85068260797&doi=10.1016%2fj.biortech.2019.121727&partnerID=40&md5=b5abf95cbe88e7aeee2030e81c0b6e3d relation: 10.1016/j.biortech.2019.121727 identifier: 10.1016/j.biortech.2019.121727