eprintid: 11277
rev_number: 2
eprint_status: archive
userid: 1
dir: disk0/00/01/12/77
datestamp: 2023-11-10 03:25:47
lastmod: 2023-11-10 03:25:47
status_changed: 2023-11-10 01:14:52
type: article
metadata_visibility: show
creators_name: Kosalishkwaran, G.
creators_name: Parasuraman, S.
creators_name: Singh, D.K.J.
creators_name: Natarajan, E.
creators_name: Elamvazuthi, I.
creators_name: George, J.
title: Measurement of range of motions of L3-L4 healthy spine through offsetting reflective markers and in silico analysis of meshed model
ispublished: pub
keywords: Biomechanics; Computerized tomography; Diagnosis; Kinematics; Medical image processing; Mesh generation; Quality control, Degenerative disc disease; Direct measurement; Elderly populations; In-silico; In-vivo experiments; Individual components; Kinesis; Lumbar spines, Risk assessment, adult; annulus fibrosus; anterior longitudinal ligament; Article; biomechanics; capsular ligament; computer assisted tomography; computer model; cortical bone; finite element analysis; fourth lumbar vertebra; human; in vivo study; interspinous ligament; intervertebral articulation; joint ligament; kinematics; ligamentum flavum; lumbar region; lumbar spine; male; measurement repeatability; mechanical stress; normal human; nucleus pulposus; posterior longitudinal ligament; priority journal; quality control; range of motion; reliability; skinfold thickness; supraspinous ligament; third lumbar vertebra; trabecular bone; transverse ligament; young adult
note: cited By 6
abstract: Degenerative disc disease (DDD) is a common condition in elderly population that can be painful and can significantly affect individual�s quality of life. Diagnosis of DDD allows prompt corrective actions but it is challenging due to the absence of any symptoms at early stages. In studying disc degeneration, measurement of the range of motion (RoM) and loads acting on the spine are crucial factors. However, direct measurement of RoM involves increased instrumentation and risk. In this paper, an innovative method is proposed for calculating RoM, emphasizing repeatability and reliability by considering the posterior thickness of the spine. This is achieved by offsetting the position of markers in relation to the actual vertebral loci. Three geometrically identical finite element models of L3-L4 are developed from a CT scan with different types of elements, and thereafter, mesh element-related metrics are provided for the assessment of the quality of models. The model with the best mesh quality is used for further analysis, where RoM are within ranges as reported in literature and in vivo experiment results. Various kinds of stresses acting on individual components including facet joints are analysed for normal and abnormal loading conditions. The results showed that the stresses in abnormal load conditions for all components including cortical (76.67 MPa), cancellous (69.18 MPa), annulus (6.30 MPa) and nucleus (0.343 MPa) are significantly greater as compared to normal loads (49.96 MPa, 44.2 MPa, 4.28 MPa and 0.23 MPa respectively). However, stress levels for both conditions are within safe limits (167�215 MPa for cortical, 46 MPa for the annulus and 3 MPa for facets). The results obtained could be used as a baseline motion and stresses of healthy subjects based on their respective lifestyles, which could benefit clinicians to suggest corrective actions for those affected by DDD. © 2019, International Federation for Medical and Biological Engineering.
date: 2019
publisher: Springer Verlag
official_url: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85071321950&doi=10.1007%2fs11517-019-02026-6&partnerID=40&md5=cbfbf7b3ff480002128e574d8f2d3729
id_number: 10.1007/s11517-019-02026-6
full_text_status: none
publication: Medical and Biological Engineering and Computing
volume: 57
number: 10
pagerange: 2305-2318
refereed: TRUE
issn: 01400118
citation:   Kosalishkwaran, G. and Parasuraman, S. and Singh, D.K.J. and Natarajan, E. and Elamvazuthi, I. and George, J.  (2019) Measurement of range of motions of L3-L4 healthy spine through offsetting reflective markers and in silico analysis of meshed model.  Medical and Biological Engineering and Computing, 57 (10).  pp. 2305-2318.  ISSN 01400118