<> "The repository administrator has not yet configured an RDF license."^^ . <> . . . "Assessment of gonadotropins and testosterone hormone levels in regular Mitragyna speciosa (Korth.) users"^^ . "Ethnopharmacological relevance: Mitragyna speciosa (Korth.) also known as kratom, is a native medicinal plant of Southeast Asia with opioid-like effects. Kratom tea/juice have been traditionally used as a folk remedy and for controlling opiate withdrawal in Malaysia. Long-term opioid use is associated with depletion in testosterone levels. Aim of the study: Since kratom is reported to deform sperm morphology and reduce sperm motility, we aimed to clinically investigate the testosterone levels following long-term kratom tea/juice use in regular kratom users. Methods: A total of 19 regular kratom users were recruited for this cross-sectional study. A full-blood test was conducted including determination of testosterone level, follicle stimulating hormone (FSH) and luteinizing hormone (LH) profile, as well as hematological and biochemical parameters of participants. Results: We found long-term kratom tea/juice consumption with a daily mitragynine dose of 76.23�94.15 mg did not impair testosterone levels, or gonadotrophins, hematological and biochemical parameters in regular kratom users. Conclusion: Regular kratom tea/juice consumption over prolonged periods (>2 years) was not associated with testosterone impairing effects in humans. © 2018 Elsevier B.V."^^ . "2018" . . "221" . . "Elsevier Ireland Ltd"^^ . . . "Journal of Ethnopharmacology"^^ . . . "03788741" . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . "M.S.A."^^ . "Chan"^^ . "M.S.A. Chan"^^ . . "S.M."^^ . "Mansor"^^ . "S.M. Mansor"^^ . . "V."^^ . "Murugaiyah"^^ . "V. Murugaiyah"^^ . . "V."^^ . "Kasinather"^^ . "V. Kasinather"^^ . . "N.J.Y."^^ . "Chear"^^ . "N.J.Y. Chear"^^ . . "S.B.S."^^ . "Hamid"^^ . "S.B.S. Hamid"^^ . . "E.T.W."^^ . "Ho"^^ . "E.T.W. Ho"^^ . . "O."^^ . "Grundmann"^^ . "O. Grundmann"^^ . . "D."^^ . "Singh"^^ . "D. Singh"^^ . . . . . "HTML Summary of #10122 \n\nAssessment of gonadotropins and testosterone hormone levels in regular Mitragyna speciosa (Korth.) users\n\n" . "text/html" . .