The presence of curvature-induced secondary flow in helical pipe which create complex transport phenomena and higher transfer rate has attracted significant attention from both academic and industry. Flow behavior and transport processes in helical tube have been intensively investigated. Nevertheless, most studies were focused on the performance based on first law of thermodynamics with limited studies concerning the performance based on second law of thermodynamics. The objective of this study is to investigate the heat transfer performance of helical tube according to both first and second law. The heat transfer rate and entropy generation of helical tubes with various cross-sections, i.e. circular, ellipse and square, subjected to constant wall heat flux conditions are numerically evaluated by utilizing computational fluid dynamics (CFD) approach. Their performances are compared to those of straight tube with identical cross-section. The results indicate that helical tube provides higher heat transfer at the cost of higher pressure. Moreover, it was found that entropy generation in helical tubes is considerably lower as compared to that in straight tube. Among the studied cross-sections, square has the highest heat transfer albeit having the highest pressure drop and entropy generation for both straight and helical tubes. © 2018 The Authors, published by EDP Sciences.