This paper is presenting results obtained from experimental investigations on engine performance and emissions using diesel/biodiesel blended with nanoparticles and compare with pure diesel/biodiesel mixture. The effect of 10 PPM iron oxides (Fe3O4) nanoparticles additive to biodiesel and neat diesel fuels in terms of engine performance and emission characteristics were experimentally investigated in a single cylinder diesel engine. The Fe3O4 nanoparticles were mixed in diesel and 20, 40 palm biodiesel blend with diesel (BD20, BD40) using ultra-sonication. These modified fuels were termed as D+10N, BD-20+10N, and BD-40+10N, respectively. Initial results indicate that the properties such as: density, viscosity, and calorific value of the fuel blends tend to increase with the addition of nanoparticles in the blends. Enhancement in engine performance has been perceived with the addition of Fe3O4 nanoparticles. Break thermal efficiency has been enhanced by about 3.16, 4.66 for BD-20 and BD-40, and about 2.06, 3.34, 4.89 for D+10N, BD-20+10N, and BD-40+10N on the pure diesel, respectively. BSFC has been lowered by 3.07 for D+10N, 1.55 for BD-20+10N, and 1.33 for BD-40+10N compared to the results of the same Diesel without nanoadditive. As the enhancement has been demonstrated, it is recommended to extend the work by measuring the same performance and emission parameters using different types of nanoadditives to the blended diesel/biodiesel. © 2018 Author(s).