Dengue is an arthropod-borne or mosquito-borne viral infection that had rapidly spread in all state of World Health Organization (WHO) in current year. There are two types of dengue most severe such as Hemorrhagic Dengue Fever and Dengue Shock Syndrome. Disease dengue and dengue hemorrhagic fever is a mysterious disease that is usually found in tropical areas with the geographic distribution similar to malaria. Dengue virus is spread by female mosquito mostly it's comes from species Aedesaegypti mosquito, there are also cases involving mosquitoes AedesAlbopictus. Climate change also contributes to the spread of the dengue virus in Malaysia such as rising temperatures, increased rainfall and humidity increased over the last four decades. In this study the climate factors such as rainfall distribution, humidity and temperature for every month are investigated towards the dengue spreading. Multiple regressions have been used to obtain the relationship between all climate factors for dengue spreading. One prediction model is proposed for State of Perak. © Published under licence by IOP Publishing Ltd.