Rate -based non-equilibrium dynamic simulation model for CO2 removal at high pressure is presented in this research. To ensure the smoothness in the operation plant for natural gas process, therefore the process control need to be designed based on the dynamics model studied. In order to successfully design a dynamic model, steady state model simulation model need to be established and in this research, Aspen Plus simulator had been utilized. The input data and information for the simulation had been acquired from the real pilot plants that operate at 15bar using structured column of FLEXIPAC 1Y. Dynamic analysis is conducted to observe the effect of changing the lean solvent flow rate and thermodynamic state on the MEA absorption column behavior. It is observed that the model satisfactorily predicts the pilot plant behavior under multiple inputs and disturbances. © 2016 The Authors. Published by Elsevier Ltd.