An experimental evaluation of CO2 solubility in aqueous sodium L-prolinate (SP) solution was carried out using high-pressure solubility equipment at three different temperatures, 303.15, 313.15, and 333.15 K. The study was conducted over the pressure range from 2 to 60 bar for 30 wt. SP solution. It was found that, the CO2 loading (mole of CO2 / mole of SP) decreases with increasing temperature, while it increases with increasing the pressure of gas. ANOVA analysis was carried out to determine the statistical significance of the solubility data with respect to temperature and pressure. The CO2 loading of aqueous SP solution was also compared with MEA and aqueous sodium glycinate (SG) solution. It was observed that the aqueous SP solution has higher CO2 loading capacity as compared to 30 wt. MEA, and comparable with aqueous 30 wt. SG solution. © 2016 The Authors.