This chapter outlines an intelligent fuzzy multi-criteria decision-making (MCDM) model for appropriate selection of a flexible manufacturing system (FMS) in a conflicting criteria environment. A holistic methodology has been developed for finding out the �optimal FMS� from a set of candidate-FMSs. This method of trade-offs among various parameters, viz., design parameters, economic considerations, etc., affecting the FMS selection process in an MCDM environment. The proposed method calculates the global priority values (GP) for functional, design factors and other important attributes by an eigenvector method of a pair-wise comparison. These GPs are used as subjective factor measures (SFMs) in determining the selection index (SI). The proposed fuzzified methodology is equipped with the capability of determining changes in the FMS selection process that results from making changes in the parameters of the model. The model achieves balancing among criteria. Relationships among the degree of fuzziness, level-of-satisfaction and the SIs of the MCDM methodology guide decision makers under a tripartite fuzzy environment in selecting their choice of trading-off with a predetermined allowable fuzziness. The measurement of level-of-satisfaction during making the appropriate selection of FMS is carried out. © Springer Science + Business Media, LLC 2008.