The present research proposes a novel approach based on matrix to determine the makespan of a batch process adopting zero wait transfer policy. The proposed approach uses simple mathematical formulae, applied on a matrix representing the batch process recipes according to a selected production sequence. Rearrangement of the matrix rows according to the varied production sequences possible for the specified batch process recipes enables the makespan to be determined for each sequence. Designer is then provided with the production sequence options with its corresponding makespan from which a selection could be made according to the process conditions. © 2008 Asian Network for Scientific Information.