The acceptance of internet as a ubiquitous mechanism for ICT activities has revolutionized e-applications. Cloud computing is a new discipline to exploit the virtual environment over the internet for applications. Cloud service providers offer large infrastructure, computing power and software services configurable by the client at low upfront cost. But the vulnerability of cyber domain has led to serious security concerns of the clients regarding services and data management. Cyber security mechanisms have evolved in the past two decades to handle these problems at data transport and operation levels. To enhance user confidence in cloud computing, end to end security, data integrity, proof of retrievablity (POR), third party audit (TPA) along with forensic methods have been proposed. The security solutions offered by trusted platform group (TPG) can be used for cloud computing through integration with trusted platform modules (TPM) embedded in the client and server machines. The scheme addresses the physical security concerns posed by the portable data access units like mobiles, notebooks, iPADs and laptops. In this paper we proposed a cyber security solution for telemedicine over the cloud architectures based on available resources. © Springer-Verlag Berlin Heidelberg 2012.