By taking the analogy with bio-molecular systems, many systems containing simple molecular entities like water could have an information storage system. This storage system is similar to a gene locus which is presumably enclosed within the nucleus of its atoms. Information are stored in the form of perhaps such kind of fundamental interactions among sub-sub-atomic particles within each nucleons, just like hydrogen bonding among the nucleotides residue in the DNA. If this is true, then small molecules, water molecules for example, might be no longer as all-identical entities, instead they might all be organisms, which each of them is individually unique in their own. Furthermore, if this could someday be comprehended, many natural phenomena which are still not well understood due to their complexity such as cloud morphology in the sky, crystallization pattern of snow flakes and crack pattern in drying clay mud, etc., could be rationalized in a fundamental way, still by using physicochemical if not nucleo-chemical principles. © 2011 Asian Network for Scientific Information.