This paper uses singular value decomposition (SVD) for studying the dynamic properties of fatigue-loaded intervertebral disc. Previously, this problem had been addressed using mathematical models of using mass, spring and damper or based on poroelastic theory. This paper utilizes the signal processing approach and attempts to describe SVD based feature that can be an indicator for change in behavioral performance of the intervertebral disc warning the occurrence of temporary or permanent change in the structure or abnormality in behavior. The results are encouraging; however, further validation is required with more data. © 2011 IEEE.