As the human population getting higher, people demand for more facilities to satisfy their daily needs. In order to fulfil their needs, people need to travel. More facilities will result in more mobility requirement by people and at the same time more travels will be done. The travel pattern of people can be best illustrated by using the space�time prism as it takes into account the distance and time of the travels performed to the required location. Increasing travels might affect the health performances of people in various condition. Several health variables such as general health, physical functioning, social functioning, etc. need to be considered while studying the effect of activity space towards health performances. The results of the study might differ or remain the same if it is conducted in two or more different places. Therefore, this paper aims to compare the effect of activity space (measured by using Euclidian distance method) on health performances (physical health and mental health) between Seri Iskandar, Perak, Malaysia and Yogyakarta, Indonesia. It is found that there is no difference in the comparison of the effect of activity space on the health performances between Malaysia and Indonesia. By conducting this study, it is expected that the outcome of the study can provide engineers and planners the information and guidance to design optimized built environment based on human travel behavior by prioritizing their health performance in each location. © 2024, Institute of Technology PETRONAS Sdn Bhd.