Many firms around the world have adopted E-commerce to enhance competitive advantage and business performance. E-commerce is now an important model in today's business environment and is often considered a key dimension in generating a firm value, despite the fact that many firms still have difficulty generating the anticipated returns of E-Commerce technology investments. To date, researchers have attempted to develop range of strategies for E-commerce success but uptake in business environments has proven slow and inconsistent. In this paper we proposed a model that offers a strategic framework for generating value from E-commerce, using technology resources factors, IT infrastructure, IT-human resources to facilitate business outcomes. A regression analysis was performed on survey data from 243 Malaysian firms. Results indicated that technology resources are the key drivers of E-commerce and lead to better business performance. © 2011 Springer-Verlag.